When I heard of urine therapy, there are two things that cross my mind.  First, the obvious gross!  I mean honestly, you pee on someone’s leg to reduce the pain of a jelly fish sting.  But you don’t pee on your face or let them pee on your face or apply urine there!  Second, this is actually more related to skincare.  They have used an ingredient called urea as a preservative and sometimes a moisturizer.  It is pee or urine as you might expect, and it has actually been shown to damage the skin, possibly due to the acidity often associated with urine in general. 

 I first heard of this, because there was a woman in a hospital who apparently was interrogated because they were sure she had to be the wrong patient as she looked younger than she was.  But apparently she took a swab of her own morning urine and dabbed it all over her face and neck.  Wouldn’t that stink later on too?  Anyway, once it dried, she used her favorite moisturizing face wash to cleanse it and then dabbed her skin dry with a towel. 

Couldn’t it be the face wash?  Apparently, it’s highly recommended for zits, which if the acidity were high enough would kill bacteria to some degree.  But it might also like urea cause skin irritation.  But in terms of wrinkles, I am highly doubtful.  They may have used it in the Renaissance period, but that’s not necessarily a good indication.